Publications

Publication Prof. Dr, Carsten Riether

Flieswasser T, Van den Eynde A, Van Audenaerde J, De Waele J, Lardon F, Riether C, de Haard H, Smits E, Pauwels P, Jacobs J. The CD70-CD27 axis in oncology: the new kids on the block. J Exp Clin Cancer Res. 2022 Jan 6;41(1):12. doi: 10.1186/s13046-021-02215-y. PMID: 34991665; PMCID: PMC8734249.

Hinterbrandner M, Rubino V, Stoll C, Forster S, Schnüriger N, Radpour R, Baerlocher GM, Ochsenbein AF, Riether C. Tnfrsf4-expressing regulatory T cells promote immune escape of chronic myeloid leukemia stem cells. JCI Insight. 2021 Dec 8;6(23):e151797. doi: 10.1172/jci.insight.151797. PMID: 34727093; PMCID: PMC8675189.

Radpour R, Stucki M, Riether C, Ochsenbein AF. Epigenetic Silencing of Immune-Checkpoint Receptors in Bone Marrow- Infiltrating T Cells in Acute Myeloid Leukemia. Front Oncol. 2021 May 4;11:663406. doi: 10.3389/fonc.2021.663406. PMID: 34017684; PMCID: PMC8130556.

Ruzgys P, Böhringer S, Dokumaci AS, Hari Y, Schürch CM, Brühl F, Schürch S, Szidat S, Riether C, Šatkauskas S, Geiser T, Hradetzky D, Gazdhar A. Electrospray Mediated Localized and Targeted Chemotherapy in a Mouse Model of Lung Cancer. Front Pharmacol. 2021 Apr 20;12:643492. doi: 10.3389/fphar.2021.643492. PMID: 33959011; PMCID: PMC8093875.

Riether C, Radpour R, Kallen NM, Bürgin DT, Bachmann C, Schürch CM, Lüthi U, Arambasic M, Hoppe S, Albers CE, Baerlocher GM, Ochsenbein AF. Metoclopramide treatment blocks CD93-signaling-mediated self-renewal of chronic myeloid leukemia stem cells. Cell Rep. 2021 Jan 26;34(4):108663. doi: 10.1016/j.celrep.2020.108663. PMID: 33503440.

Amrein MA, Bührer ED, Amrein ML, Li Q, Rothschild S, Riether C, Jaggi R, Savic-Prince S, Bubendorf L, Gautschi O, Ochsenbein AF. Chemotherapy negatively impacts the tumor immune microenvironment in NSCLC: an analysis of pre- and post-treatment biopsies in the multi-center SAKK19/09 study. Cancer Immunol Immunother. 2021 Feb;70(2):405-415. doi: 10.1007/s00262-020-02688-4. Epub 2020 Aug 7. PMID: 32767058; PMCID: PMC7889678.

Brigger D, Riether C, van Brummelen R, Mosher KI, Shiu A, Ding Z, Zbären N, Gasser P, Guntern P, Yousef H, Castellano JM, Storni F, Graff-Radford N, Britschgi M, Grandgirard D, Hinterbrandner M, Siegrist M, Moullan N, Hofstetter W, Leib SL, Villiger PM, Auwerx J, Villeda SA, Wyss-Coray T, Noti M, Eggel A. Eosinophils regulate adipose tissue inflammation and sustain physical and immunological fitness in old age. Nat Metab. 2020 Aug;2(8):688-702. doi: 10.1038/s42255-020-0228-3. Epub 2020 Jul 6. PMID: 32694825; PMCID: PMC7438316.

Riether C, Pabst T, Höpner S, Bacher U, Hinterbrandner M, Banz Y, Müller R, Manz MG, Gharib WH, Francisco D, Bruggmann R, van Rompaey L, Moshir M, Delahaye T, Gandini D, Erzeel E, Hultberg A, Fung S, de Haard H, Leupin N, Ochsenbein AF. Targeting CD70 with cusatuzumab eliminates acute myeloid leukemia stem cells in patients treated with hypomethylating agents. Nat Med. 2020 Sep;26(9):1459-1467. doi: 10.1038/s41591-020-0910-8. Epub 2020 Jun 29. PMID: 32601337.

Frangež Ž, Fernández-Marrero Y, Stojkov D, Seyed Jafari SM, Hunger RE, Djonov V, Riether C, Simon HU. BIF-1 inhibits both mitochondrial and glycolytic ATP production: its downregulation promotes melanoma growth. Oncogene. 2020 Jun;39(26):4944-4955. doi: 10.1038/s41388-020-1339-8. Epub 2020 Jun 3. PMID: 32493957.

Riether C, Ochsenbein AF. Genetic Alterations Impact Immune Microenvironment Interactions in Follicular Lymphoma. Cancer Cell. 2020 May 11;37(5):621-622. doi: 10.1016/j.ccell.2020.04.008. PMID: 32396854.

Jaeger-Ruckstuhl CA, Hinterbrandner M, Höpner S, Correnti CE, Lüthi U, Friedli O, Freigang S, Al Sayed MF, Bührer ED, Amrein MA, Schürch CM, Radpour R, Riether C, Ochsenbein AF. TNIK signaling imprints CD8+ T cell memory formation early after priming. Nat Commun. 2020 Apr 2;11(1):1632. doi: 10.1038/s41467-020-15413-7. PMID: 32242021; PMCID: PMC7118140.

Liu H, He Z, Germič N, Ademi H, Frangež Ž, Felser A, Peng S, Riether C, Djonov V, Nuoffer JM, Bovet C, Mlinarič-Raščan I, Zlobec I, Fiedler M, Perren A, Simon HU. ATG12 deficiency leads to tumor cell oncosis owing to diminished mitochondrial biogenesis and reduced cellular bioenergetics. Cell Death Differ. 2020 Jun;27(6):1965-1980. doi: 10.1038/s41418-019-0476-5. Epub 2019 Dec 16. PMID: 31844253; PMCID: PMC7244572.

Salomé B, Gomez-Cadena A, Loyon R, Suffiotti M, Salvestrini V, Wyss T, Vanoni G, Ruan DF, Rossi M, Tozzo A, Tentorio P, Bruni E, Riether C, Jacobsen EM, Jandus P, Conrad C, Hoenig M, Schulz A, Michaud K, Della Porta MG, Salvatore S, Ho PC, Gfeller D, Ochsenbein A, Mavilio D, Curti A, Marcenaro E, Steinle A, Horowitz A, Romero P, Trabanelli S, Jandus C. CD56 as a marker of an ILC1-like population with NK cell properties that is functionally impaired in AML. Blood Adv. 2019 Nov 26;3(22):3674-3687. doi: 10.1182/bloodadvances.2018030478. PMID: 31765481; PMCID: PMC6880898.

Mohsen MO, Vogel M, Riether C, Muller J, Salatino S, Ternette N, Gomes AC, Cabral-Miranda G, El-Turabi A, Ruedl C, Kundig TM, Dermime S, Knuth A, Speiser DE, Bachmann MF. Targeting Mutated Plus Germline Epitopes Confers Pre-clinical Efficacy of an Instantly Formulated Cancer Nano-Vaccine. Front Immunol. 2019 May 15;10:1015. doi: 10.3389/fimmu.2019.01015. PMID: 31156619; PMCID: PMC6532571.

Mohsen MO, Heath MD, Cabral-Miranda G, Lipp C, Zeltins A, Sande M, Stein JV, Riether C, Roesti E, Zha L, Engeroff P, El-Turabi A, Kundig TM, Vogel M, Skinner MA, Speiser DE, Knuth A, Kramer MF, Bachmann MF. Vaccination with nanoparticles combined with micro-adjuvants protects against cancer. J Immunother Cancer. 2019 Apr 26;7(1):114. doi: 10.1186/s40425-019-0587-z. Erratum in: J Immunother Cancer. 2019 May 23;7(1):137. PMID: 31027511; PMCID: PMC6485085.

Radpour R, Riether C, Simillion C, Höpner S, Bruggmann R, Ochsenbein AF. CD8+ T cells expand stem and progenitor cells in favorable but not adverse risk acute myeloid leukemia. Leukemia. 2019 Oct;33(10):2379-2392. doi: 10.1038/s41375-019-0441-9. Epub 2019 Mar 15. PMID: 30877275.

All publications: https://pubmed.ncbi.nlm.nih.gov/?term=Riether%20C&sort=date