2021
Hill V, Akarsu H, Barbarroja RS, Cippà VL, Kuhnert P, Heller M, Falquet L, Heller M, Stoffel MH, Labroussaa F, Jores J. Minimalistic mycoplasmas harbor different functional toxin-antitoxin systems. PLoS Genet. 2021 Oct 21;17(10):e1009365. doi: 10.1371/journal.pgen.1009365. PMID: 34673769; PMCID: PMC8562856.
Anghel N, Müller J, Serricchio M, Jelk J, Bütikofer P, Boubaker G, Imhof D, Ramseier J, Desiatkina O, Păunescu E, Braga-Lagache S, Heller M, Furrer J, Hemphill A. Cellular and Molecular Targets of Nucleotide-Tagged Trithiolato-Bridged Arene Ruthenium Complexes in the Protozoan Parasites Toxoplasma gondii and Trypanosoma brucei. Int J Mol Sci. 2021 Oct 5;22(19):10787. doi: 10.3390/ijms221910787. PMID: 34639127; PMCID: PMC8509533.
Schniering J, Maciukiewicz M, Gabrys HS, Brunner M, Blüthgen C, Meier C, Braga-Lagache S, Uldry AC, Heller M, Guckenberger M, Fretheim H, Nakas CT, Hoffmann-Vold AM, Distler O, Frauenfelder T, Tanadini-Lang S, Maurer B. Computed tomography-based radiomics decodes prognostic and molecular differences in interstitial lung disease related to systemic sclerosis. Eur Respir J. 2021 Oct 14:2004503. doi: 10.1183/13993003.04503-2020. Epub ahead of print. PMID: 34649979.
Zysset-Burri DC, Schlegel I, Lincke JB, Jaggi D, Keller I, Heller M, Lagache SB, Wolf S, Zinkernagel MS. Understanding the Interactions Between the Ocular Surface Microbiome and the Tear Proteome. Invest Ophthalmol Vis Sci. 2021 Aug 2;62(10):8. doi: 10.1167/iovs.62.10.8. PMID: 34369983; PMCID: PMC8354087.
Hallal M, Braga-Lagache S, Jankovic J, Simillion C, Bruggmann R, Uldry AC, Allam R, Heller M, Bonadies N. Inference of kinase-signaling networks in human myeloid cell line models by Phosphoproteomics using kinase activity enrichment analysis (KAEA). BMC Cancer. 2021 Jul 8;21(1):789. doi: 10.1186/s12885-021-08479-z. PMID: 34238254; PMCID: PMC8268341.
Contu L, Balistreri G, Domanski M, Uldry AC, Mühlemann O. Characterisation of the Semliki Forest Virus-host cell interactome reveals the viral capsid protein as an inhibitor of nonsense-mediated mRNA decay. PLoS Pathog. 2021 May 21;17(5):e1009603. doi: 10.1371/journal.ppat.1009603. PMID: 34019569; PMCID: PMC8174725.
Müller J, Heller M, Uldry AC, Braga S, Müller N. Nitroreductase Activites in Giardia lamblia: ORF 17150 Encodes a Quinone Reductase with Nitroreductase Activity. Pathogens. 2021 Jan 27;10(2):129. doi: 10.3390/pathogens10020129. PMID: 33513906; PMCID: PMC7912051.
Bevkal S, Naguleswaran A, Rehmann R, Kaiser M, Heller M, Roditi I. An Alba-domain protein required for proteome remodelling during trypanosome differentiation and host transition. PLoS Pathog. 2021 Jan 25;17(1):e1009239. doi: 10.1371/journal.ppat.1009239. PMID: 33493187; PMCID: PMC7861527.
Tamò L, Fytianos K, Caldana F, Simillion C, Feki A, Nita I, Heller M, Geiser T, Gazdhar A. Interactome Analysis of iPSC Secretome and Its Effect on Macrophages In Vitro. Int J Mol Sci. 2021 Jan 19;22(2):958. doi: 10.3390/ijms22020958. PMID: 33478018; PMCID: PMC7835982.
2020
Bartos K, Ramakrishnan SK, Braga-Lagache S Hänzi B, Durussel F, Sridharan AK, Zhu Y, Sheehan D, Hynes NE, Bonny O, Moor MB. (2020) Redox protein Memo1 coordinates FGF23-driven signaling and small Rho-GTPases in the mouse kidney. bioRxiv 2020.12.04.402511. doi.org/10.1101/2020.12.04.402511.
Heller M, Braga S, Müller N, Müller J. Transfection With Plasmid Causing Stable Expression of a Foreign Gene Affects General Proteome Pattern in Giardia lamblia Trophozoites. Front Cell Infect Microbiol. 2020 Dec 18;10:602756. doi: 10.3389/fcimb.2020.602756. PMID: 33392107; PMCID: PMC7775365.
Cyrta J, Augspach A, De Filippo MR, Prandi D, Thienger P, Benelli M, Cooley V, Bareja R, Wilkes D, Chae SS, Cavaliere P, Dephoure N, Uldry AC, Lagache SB, Roma L, Cohen S, Jaquet M, Brandt LP, Alshalalfa M, Puca L, Sboner A, Feng F, Wang S, Beltran H, Lotan T, Spahn M, Kruithof-de Julio M, Chen Y, Ballman KV, Demichelis F, Piscuoglio S, Rubin MA. Role of specialized composition of SWI/SNF complexes in prostate cancer lineage plasticity. Nat Commun. 2020 Nov 3;11(1):5549. doi: 10.1038/s41467-020-19328-1. PMID: 33144576; PMCID: PMC7642293.
Duman M, Vaquié A, Nocera G, Heller M, Stumpe M, Siva Sankar D, Dengjel J, Meijer D, Yamaguchi T, Matthias P, Zeis T, Schaeren-Wiemers N, Hayoz A, Ruff S, Jacob C. EEF1A1 deacetylation enables transcriptional activation of remyelination. Nat Commun. 2020 Jul 9;11(1):3420. doi: 10.1038/s41467-020-17243-z. PMID: 32647127; PMCID: PMC7347577.
Winzer P, Müller J, Imhof D, Ritler D, Uldry AC, Braga-Lagache S, Heller M, Ojo KK, Van Voorhis WC, Ortega-Mora LM, Hemphill A. Neospora caninum: Differential Proteome of Multinucleated Complexes Induced by the Bumped Kinase Inhibitor BKI-1294. Microorganisms. 2020 May 26;8(6):801. doi: 10.3390/microorganisms8060801. PMID: 32466554; PMCID: PMC7355844.
Müller J, Braga S, Uldry AC, Heller M, Müller N. Comparative proteomics of three Giardia lamblia strains: investigation of antigenic variation in the post-genomic era. Parasitology. 2020 Aug;147(9):1008-1018. doi: 10.1017/S0031182020000657. Epub 2020 Apr 27. PMID: 32338227; PMCID: PMC7332775.
Briand ML , Gebleux R , Richina F , Correro MR , Grether Y , Dudal Y , Braga-Lagache S , Heller M , Beerli RR , Grawunder U , Corvini PF , Shahgaldian P . Partially shielded enzymes capable of processing large protein substrates. Chem Commun (Camb). 2020 May 11;56(38):5170-5173. doi: 10.1039/d0cc01150a. Epub 2020 Apr 8. PMID: 32266896.
Cosgrove J, Novkovic M, Albrecht S, Pikor NB, Zhou Z, Onder L, Mörbe U, Cupovic J, Miller H, Alden K, Thuery A, O'Toole P, Pinter R, Jarrett S, Taylor E, Venetz D, Heller M, Uguccioni M, Legler DF, Lacey CJ, Coatesworth A, Polak WG, Cupedo T, Manoury B, Thelen M, Stein JV, Wolf M, Leake MC, Timmis J, Ludewig B, Coles MC. B cell zone reticular cell microenvironments shape CXCL13 gradient formation. Nat Commun. 2020 Jul 22;11(1):3677. doi: 10.1038/s41467-020-17135-2. PMID: 32699279; PMCID: PMC7376062.
2019
Nasher F, Kwun MJ, Croucher NJ, Heller M, Hathaway LJ. Peptide Occurring in Enterobacteriaceae Triggers Streptococcus pneumoniae Cell Death. Front Cell Infect Microbiol. 2019 Sep 10;9:320. doi: 10.3389/fcimb.2019.00320. PMID: 31552200; PMCID: PMC6748166.
Müller J, Braga S, Heller M, Müller N. Resistance formation to nitro drugs in Giardia lamblia: No common markers identified by comparative proteomics. Int J Parasitol Drugs Drug Resist. 2019 Apr;9:112-119. doi: 10.1016/j.ijpddr.2019.03.002. Epub 2019 Mar 15. PMID: 30889439; PMCID: PMC6423486.
Kuhn-Nentwig L, Langenegger N, Heller M, Koua D, Nentwig W. The Dual Prey-Inactivation Strategy of Spiders-In-Depth Venomic Analysis of Cupiennius salei. Toxins (Basel). 2019 Mar 19;11(3):167. doi: 10.3390/toxins11030167. PMID: 30893800; PMCID: PMC6468893.
Kehl D, Generali M, Mallone A, Heller M, Uldry AC, Cheng P, Gantenbein B, Hoerstrup SP, Weber B. Proteomic analysis of human mesenchymal stromal cell secretomes: a systematic comparison of the angiogenic potential. NPJ Regen Med. 2019 Apr 16;4:8. doi: 10.1038/s41536-019-0070-y. PMID: 31016031; PMCID: PMC6467904.
Zahnd S, Braga-Lagache S, Buchs N, Lugli A, Dawson H, Heller M, Zlobec I. A Digital Pathology-Based Shotgun-Proteomics Approach to Biomarker Discovery in Colorectal Cancer. J Pathol Inform. 2019 Dec 12;10:40. doi: 10.4103/jpi.jpi_65_18. PMID: 31921488; PMCID: PMC6939342.
Nicholson P, Furrer J, Hässig M, Strauss C, Heller M, Braga-Lagache S, Frey J. Production of neutralizing antibodies against the secreted Clostridium chauvoei toxin A (CctA) upon blackleg vaccination. Anaerobe. 2019 Apr;56:78-87. doi: 10.1016/j.anaerobe.2019.02.011. Epub 2019 Feb 14. PMID: 30771460.
Brunner MAT, Rüfenacht S, Bauer A, Erpel S, Buchs N, Braga-Lagache S, Heller M, Leeb T, Jagannathan V, Wiener DJ, Welle MM. Bald thigh syndrome in sighthounds-Revisiting the cause of a well-known disease. PLoS One. 2019 Feb 22;14(2):e0212645. doi: 10.1371/journal.pone.0212645. PMID: 30794648; PMCID: PMC6386255.
Jack T, Leuenberger M, Ruepp MD, Vernekar SKV, Thompson AJ, Braga-Lagache S, Heller M, Lochner M. Mapping the Orthosteric Binding Site of the Human 5-HT3 Receptor Using Photo-cross-linking Antagonists. ACS Chem Neurosci. 2019 Jan 16;10(1):438-450. doi: 10.1021/acschemneuro.8b00327. Epub 2018 Sep 11. PMID: 30149702.
2018 and older
Please follow this link for a list of publications: https://www.pmscf.dbmr.unibe.ch/research/publications/
