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Antibiotic resistance is one of the biggest threats to human health; the yearly death toll due to multidrug resistant infections is high, ca. 25,000 people in Europe, 23,000 in the US, and 700,000 around the world. The core of laboratory research is to conceive, elaborate and test innovative strategies to combat the big threat of antibiotic resistance. Over the last decade, we developed a comprehensive translational research pipeline to improve the management of critically ill patients with complex and/or hard to treat bacterial infections within the Intensive Care Unit (ICU), with the goal to better prevent, understand, diagnose, and treat them while predicting their outcome.
