The Department for BioMedical Research (DBMR) of the Faculty of Medicine of the University of Bern, led by Prof. Mark A. Rubin, MD, was established in 1994 by the University of Bern and the Inselspital (Bern University Hospital). The DBMR is divided in 13 Research Programs with about 100 participating individual labs and several Independent Research Labs whose research spans across all biomedical fields. To realize its mission to bridge the gap between bench and bedside, the DBMR promotes an integrative perspective to clinical research with a strong emphasis in the development of translational approaches, the use of omics and other cutting-edge technologies, and extensive interaction and collaboration between laboratory-based and patient-oriented clinical research. The DBMR is also committed to fostering the careers of young academics.
Congratulations to our researchers, who are once again among the most cited in the world.
A project by Prof. Mark Rubin and Dr. Anke Augspach (DBMR), Prof. Kanadia (Univ. of Connecticut), and Prof. Rätsch (ETHZ) has received the prestigious Challenge Award from the Prostate Cancer Foundation. This multidisciplinary team has received $1 mio to study the mechanisms of minor intron splicing and how inhibiting its machinery can create a new cancer specific vulnerability.
Mark Rubin talks with Alicia Morgans, GU Medical Oncologist from the Dana Farber Cancer Institute, about emerging therapies and emerging therapeutic targets in prostate cancer.
The DBMR warmly encourages its members to participate in the Basic Program (Grundprogramm) of the National Future Day, Thursday 10 November 2022. The DBMR would be delighted to welcome any pupil from 5th to 7th grade accompanied by a DBMR member!
Please see for more information (in German).
Article in Cancer Cell "Clinical application of advanced multi-omics tumor profiling: shaping precision oncology of the future":
Dr. Dilara Akhoundara and Prof. Mark A. Rubin (University of Bern / Inselspital) provide an overview of the latest technologies in precision oncology. Translating these into clinical application is still a major challenge. With research projects, the Bern Center for Precision Medicine (BCPM) contributes to bringing technological progress to the patient.
Ahead of the Night of Research around the University main building, there will be a Public Opening Event (in German) at the new research building at Murtenstrasse 24-28 between 1 and 4 pm. Three guided tours will be carried out every 30 minutes through different parts of the building (DBMR Core Facilities, virtual tour of Forensic Medicine and building technology). Please see for more details.
Urology research and clinical care at the DBMR and Insel has been recognized as an EPCCE by the European Association of Urology. Our congratulations to the Department of Urology and the urology research groups in the DBMR!
Congratulations to Marco Osterwalder, Christian Zuppinger, Andrew Macpherson, and Fabian Blank on receiving funding for their projects to reduce animal testing.
At the DBMR Day of BioMedical Research on 6 July 2022, Prof. Dr. Volker Enzmann announced the winner of the Johanna Dürmüller-bol DBMR Research Award 2022. The DBMR congratulates Emma Britt Hodcroft, PhD, this year’s winner, for her project “Investigating the impact of pandemic restrictions on circulation and genetic diversity of a respiratory virus”.
At the DBMR BioMedical Research Day on 6 July 2022, the following researchers were awarded a poster prize
Liana Hayrapetyan, Maria Natalia Rojas Velazquez, Cosima Meret Schmid, Tim Rollenske, Chantal Bachmann, Charlotte Kern
The first TANDEM grant call received 28 applications from clinician-basic researcher pairs across Switzerland, each jointly addressing a question of direct clinical relevance, from two angles: that of understanding molecular mechanism and of directly improving cancer patient care. The awardees include Prof. Marianna Kruithof-de Julio and Dr. Bernhard Kiss, DBMR, Program Cancer Therapy Resistance CTR, Kruithof-de Julio Lab.
A prestigious grant from the USA goes to the biomedical scientist Sven Rottenberg, University of Bern, and the clinical scientist Intidhar Labidi-Galy, University of Geneva and University Hospital of Geneva. They received a joint grant from the "Congressionally Directed Medical Research Programs" for their project on ovarian cancer. This underlines the high quality of the collaborative research on ovarian cancer in Bern and Geneva.
Congratulation to the DBMR Precision Medicine & Prostate Cancer Researcher! In the largest cohort of prostate cancer brain metastases yet studied, researchers at the DBMR led a pan-Swiss study that demonstrated that these metastases harbor common genetic alterations that may benefit from existing PARPi therapy.
Congress Society of Reproductive Investigation, USA, March 2022
Congratulation to our researchers Patricia Renz, Anda-Petronela Radan, Mafalda Trippel, Valérie Haesler, Luigi Raio, Daniel Surbek who received President's Presenter's Award for an outstanding Abstract effectively furthering the objectives of the Society. Title: Immunohistochemical evidence of SARS-CoV-2 in the placenta after infection during pregnancy: A prospective case-control study
Congress Society of Reproductive Investigation, USA, March 2022
Congratulation to our researchers Amanda Brosius Lutz, Patricia Renz, Valérie Haesler, Vera Tscherrig, Shane Liddelow, Andreina Schoeberlein, Daniel Surbek who received an award for "Best New Investigator Poster Presentation". Title: Investigating reactive astrocytes as therapeutic targets in acute perinatal white matter injury
Congratulations to Dr. Dilara Akhoundova for receiving a fellowship from the Nuovo-Soldati Foundation for her project on targeting of homologous recombination deficiency in prostate cancer using in vitro models.
At the Opening Symposium of the DBMR on 18 March 2022, Prof. Dr. Anne Angelillo-Scherrer announced the winner of the Johanna Dürmüller-Bol DBMR Research Award 2021. The DBMR congratulates Dr. Joel Zindel, this year’s winner.
At the event celebrating the new premises of the DBMR on March 2022, PD. Dr. Michaela Medova announced the winner of the Benoît Pochon Prize 2021. The DBMR congratulates Dr. Noëlle A. Dommann, this year’s winner.
A research group led by Alexander Eggel from the Department for BioMedical Research (DBMR) at the University of Bern and the Department of Rheumatology and Immunology, Inselspital, Bern University Hospital, together with Thomas Kaufmann from the Institute of Pharmacology at the University of Bern, has now developed an allergy test that, on the one hand, greatly simplifies diagnosis and, on the other hand, can reliably predict the success of immunotherapy. The test was recently presented in a publication of the Journal of Allergy and Clinical Immunology.
On March 18, the DBMR celebrates the opening of the new DBMR premises and Core Facilities at Murtenstrasse 24-28 with a scientific mini-symposium. The event will be held at the Maurice E. Müller Auditorium, Inselspital and will start at 13.30. It will be followed by an apéro in the new DBMR Building at Murtenstrasse 24-28, which will start at 16.15.
Congratulations to Dr. Felix Baier. For the first time, the InnovationOffice of the University of Bern has awarded four "UniBE Venture Fellowships" to support entrepreneurial young researchers and their promising innovation projects. Dr. Felix Baier received the "UniBE Venture Fellowship" for a new therapeutic method to treat liver disease.
Congratulations to Prof. Mark A. Rubin on receiving a Cancer Research Grant from Werner and Hedy Berger - Janser Foundation for his project on molecular characterization, in vitro modelling and therapeutic targeting of prostate cancer liver metastases.
Congratulations to Prof. Dr. Ziad Al Nabhani on receiving the Helmut Horten Foundation Grant for his project on the influence of child intestinal microbiota on lifelong immunity.
Congratulations to Dr. Dilara Akhoundova on receiving a research grant from the Kurt and Senta Herrmann Foundation for her project on targeting of homologous recombination deficiency in prostate cancer using in vitro models.
Congratulations to Prof. Mark A. Rubin on receiving a Translational Research Grant from the ISREC Foundation for his project on advanced in vitro models of prostate cancer metastases.
Congratulations to Prof. Dr. Stephanie Ganal-Vonarburg, Dr. Julien Limenitakis and Dr. Hai Li on receiving the Pfizer Research Prize, one of the most important research prizes for medicine in Switzerland.
Congratulations! The Best Poster Award at the 2nd AACR-KCA Joint Conference on Precision Medicine in Solid Tumors, which was held on November 12, 2021 goes to Liana Hayrapetyan, Program Translational Cancer Research, Medova Lab.
Congratulations to our researchers, who are again among the world's most cited in medicine.
An international team led by Researchers from the DBMR and Inselspital show how the intestinal immune system specifically recognizes our commensal bacteria and how IgA constrains microbial fitness in the intestine. The findings expand our fundamental understanding of mucosal antibody responses and how we keep homeostasis between the host and its microbiota.
Congratulations to PD Dr. Marianna Kruithof-de Julio and Prof. Dr. Eliane J. Müller on each receiving a SNF Sinergia Grant.
Herzliche Gratulation zum Vontobel-Preis für Alter(n)sforschung dotiert mit CHF 5'000. Daniel Brigger, Alexander Eggel vom und Mario Noti (ehem. #unibern) ist es gelungen zwei altersbedingte Beeinträchtigungen mit einer neuartigen Zelltherapie zu entschleunigen.
At the outset of the May 3 DBMR Research Conference, Prof. Dr. med. Daniel M. Aebersold announced the winners of the 2020 Benoît Pochon Prize.
The prize went to Dr. med. Haitang Yang and Dr. Nicolas Melin. The DBMR congratulates the two winners. Read more
We welcome Prof. Anne Angelillo-Scherrer (Deputy Director), Dr. Marianna Kruithof-de Julio, Prof. Volker Enzmann and Prof. Carsten Riether to the DBMR Board of Directors for a period of two years and look forward to the involvement of active research members of the DBMR in the inter-workings of the department!
The contractual negotiations between swissuniversities and Springer Nature Verlag have finally been concluded, so we were able to license Nature Cancer and access is possible at https://www.nature.com/natcancer/.
Researchers at the University of Bern led an international team that has identified a novel vulnerability in advanced prostate cancer that is no longer responding to hormonal therapy. These findings could lead to the development of new treatment approaches for men suffering from the most aggressive form of prostate cancer.
Congratulations to Dr Marianna Kruithof-de-Julio and Prof. Mark Rubin, DBMR, on their 3Rs project award. With this 3RCC funding they will develop a platform for GU cancer patient-derived organoids.
Erste multizentrische Studie der Lunge zu oft auftretenden Langzeitschäden bei Ex-COVID-19 Patienten startet unter Leitung von PD. Manuela Funke-Chambour am Universitätsspital Bern. Kooperation mit @Unispital_USZ, @KantonsspitalSG u.a.m. ist vorgesehen.
+41 31 684 04 02